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McCourt, P., Gallo-Ebert, C., Gonghong, Y., Jiang, Y. & Nickels, J.T., Jr. 2013. PP2A(Cdc55) regulates G1 cyclin stability. Cell Cycle 12, 1201-1210.. PMID: 23518505
Gallo-Ebert, C., Donigan, M., Liu, H.Y., Pascual, F., Manners, M., Pandya, D., Swanson, R., Gallagher, D., Chen, W., Carman, G.M. & Nickels, J.T., Jr. 2013. The yeast anaerobic response element AR1b regulates aerobic antifungal drug-dependent sterol gene expression. J Biol Chem 288, 35466-35477.. PMID: 24163365
Yang, M., Liu, W., Pellicane, C., Sahyoun, C., Joseph, B.K., Gallo-Ebert, C., Donigan, M., Pandya, D., Giordano, C., Bata, A. & Nickels, J.T., Jr. 2013. Identification of miR-185 as a regulator of de novo cholesterol biosynthesis and low density lipoprotein uptake. J Lipid Res 55, 226-238.. PMID: 24296663
Gallo-Ebert, C., McCourt, P.C., Donigan, M., Villasmil, M.L., Chen, W., Pandya, D., Franco, J., Romano, D., Chadwick, S.G., Gygax, S.E. & Nickels, J.T., Jr. 2012. Arv1 lipid transporter function is conserved between pathogenic and nonpathogenic fungi. Fungal Genet Biol 49, 101-113.. PMID: 22142782
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Karla K. Frietze, Alyssa M. Brown, Dividutta Das, Raymond G. Franks, Jessie Lee Cunningham, Michael Hayward, Joseph T. Nickels. 2022. Lipotoxicity reduces Rig-1 expression and activity leading to impaired autophagy and cell death. Autophagy, 2022, VOL. 18, NO. 1, 142–160 https://doi.org/10.1080/15548627.2021.1920818.
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Muhua Yang, Christina Gallo-Ebert, Michael Hayward, Weidong Liu, Virginia McDonough and Joseph T. Nickels, Jr. 2020. Human insulin growth factor 2 mRNA binding protein 2 increases miR-33a/b inhibition of liver ABCA1 expression and alters low-density apolipoprotein levels in mice Mol and Cell Biol. 2020 Aug; 40(16): e00058-20. DIO: https://doi.org/10.1128%2FMCB.00058-20.
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Morgan J, McCourt P, Rankin L, Swain E, Rice LM, and Nickels Jr. JT. 2009. Altering sphingolipid metabolism in yeast cells lacking the amphiphysin ortholog, Rvs161, re-initiates sugar transporter endocytosis. Eukaryot Cell, 8(5): 779-789. PMID: 19286982
McCourt P, Morgan J, Nickels Jr. JT. 2009. Stress-induced ceramide-activated protein phosphatase can compensate for loss of amphipysin-like activity in Saccharomyces cerevisiae and functions to reinitiate endocytosis. J Biol Chem, 284(18): 11930-11941. PMID: 19254955
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Hilbert DW, Paulish TE, Mordechai E, Adelson ME, and Trama JP. 2008. O serogroups, phylogeny, and virulence factors of cervicovaginal and rectal Escherichia coli isolates. Eur J Clin Microb Infect Dis. 27(12): 1265-8. PMID: 18584221
Libby EK, Pascal KE, Mordechai E, Adelson ME, Trama JP. 2008. Atopobium vaginae triggers an innate immune response in an in vitro model of bacterial vaginosis. Microb Infect, 10(4):439-446. PMID: 18403235
Hilbert DW, Pascal KE, Libby EK, Mordechai E, Adelson ME, Trama JP. 2008. Uropathogenic Escherichia coli dominantly suppresses the innate immune response of bladder epithelial cells by a lipopolysaccharide- and Toll-like receptor 4-independent pathway. Microb Infect, 10(2):114-21. PMID: 18248759
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Vermitsky JP, Self MJ, Chadwick SG, Trama JP, Mordechai E, Adelson ME. 2007. A survey of vaginal flora Candida species isolates from women of different age groups by use of species-specific PCR detection. J Clin Microbiol, 46(4):1501-1503. PMID: 18305136
Gygax SE, Schuyler JA, Trama JP, Mordechai E, Adelson ME. 2007. The detection of erythromycin and clindamycin resistance genes in both Group B Streptococcal clinical isolates and cervicovaginal/rectal swabs. Microb Drug Resist, 13(2):119-123. PMID: 17650964
Trama JP, Pascal KE, Zimmerman JA, Self MJ, Mordechai E, Adelson ME. 2007. Identification and genotyping of Molluscum Contagiosum virus from genital swab samples by Real-Time PCR and Pyrosequencing. J Clin Virol, 40(4):325-329. PMID: 17997134
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Loa CC, Mordechai E, Tilton RC, Adelson ME. 2006. Production of recombinant Bartonella henselae 17 kDa protein for antibody-capture enzyme-linked immunosorbent assay. Diagn Microbiol Infect Dis, 55(1):1-7 . PMID: 16490335
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Gabitova-Cornell L, Surumbayeva A, Peri S, Franco-Barraza J, Restifo D, Weitz N, Ogier C, Goldman AR, Hartman TR, Francescone R, Tan Y, Nicolas E, Shah N, Handorf EA, Cai KQ, O'Reilly AM, Sloma I, Chiaverelli R, Moffitt RA, Khazak V, Fang CY, Golemis EA, Cukierman E, Astsaturov I. 2020. Cholesterol Pathway Inhibition Induces TGF-? Signaling to Promote Basal Differentiation in Pancreatic Cancer. Cancer Cell 38(4):567-583. e11. doi: 10.1016/j.ccell.2020.08.015. Epub 2020 Sep 24. PMID: 32976774
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Kato-Stankiewicz J, Hakimi I, Zhi G, Zhang J, Serebriiskii I, Guo L, Edamatsu H, Koide H, Menon S, Eckl R, Sakamuri S, Lu Y, Chen QZ, Agarwal S, Baumbach WR, Golemis EA, Tamanoi F, Khazak V. 2002. Inhibitors of Ras/Raf-1 interaction identified by two-hybrid screening revert Ras-dependent transformation phenotypes in human cancer cells. Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14398-403..
Pallai, R., A. Bhaskar, N. Barnett-Bernodat, C. Gallo-Ebert, J. T. Nickels, Jr., and L. M. Rice. 2015. Cancerous inhibitor of protein phosphatase 2A promotes premature chromosome segregation and aneuploidy in prostate cancer cells through association with shugoshin. Tumour Biol 36:6067-6074. PMID: 25736928
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Huang, L.P., Savoly, D., Sidi, A.A., Adelson, M.E., Mordechai, E. & Trama, J.P. 2012. CIP2A protein expression in high-grade, high-stage bladder cancer. Cancer Med 1, 76-81. PMID: 23342256
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Stemmer, S.M., Adelson, M.E., Trama, J.P., Dorak, M.T. & Mordechai, E. 2012. Detection rates of trichomonas vaginalis, in different age groups, using real-time polymerase chain reaction. J Low Genit Tract Dis 16, 352-357. PMID: 22968052
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Decker DE, Skutnik D, Burr J, Pattison C, Cooley-Themm C, Linn DM, & Linn CL. 2018. 2018. GDF-15 Levels increase in Aqueous Humor Following Hypertonic Saline Injection into the Episcleral Vein in a Rat Claucoma Model. IOVS July 2018. 59, 3504..
Kolb SJ, Coffey CS, Yankey JW, Krosschell K, Arnold WD, Rutkove SB, Swoboda KJ, Reyna SP, Sakonju A, Darras BT, Shell R, Kuntz N, Castro D, Parsons J, Connolly AM, Chiriboga CA, McDonald C, Burnette WB, Werner K, Thangarajh M, Shieh PB, Finanger E, Cudkowicz ME, McGovern MM, McNeil DE, Finkel R, Iannaccone ST, Kaye E, Kingsley A, Renusch SR, McGovern VL, Wang X, Zaworski PG, Prior TW, Burghes AHM, Bartlett A, Kissel JT. 2017. NeuroNEXT Clinical Trial Network on behalf of the NN101 SMA Biomarker Investigators. Natural history of infantile-onset spinal muscular atrophy. Ann Neurol. 2017 Dec;82(6):883-891. doi: 10.1002/ana.25101. Epub 2017 Dec 8. Free PMC article. Clinical Trial..
Zaworski P, von Herrmann KM, Taylor S, Sunshine SS, McCarthy K, Risher N, Newcomb T, Weetall M, Prior TW, Swoboda KJ, Chen KS, Paushkin S. 2016. SMN Protein Can Be Reliably Measured in Whole Blood with an Electrochemiluminescence (ECL) Immunoassay: Implications for Clinical Trials PLoS ONE 11(3): e0150640.. PMID: 26953792
Kolb SJ, Coffey CS, Yankey JW, Krosschell K, Arnold WD, Rutkove SB, Swoboda KJ, Reyna SP, Sakonju A, Darras BT, Shell R, Kuntz N, Castro D, Iannaccone ST, Parsons J, Connolly AM, Chiriboga CA, McDonald C, Burnette WB, Werner K, Thangarajh M, Shieh PB, Finanger E, Cudkowicz ME, McGovern MM, McNeil DE, Finkel R, Kaye E, Kingsley A, Renusch SR, McGovern VL, Wang X, Zaworski PG, Prior TW, Burghes AHM, Bartlett A, Kissel JT, and the NeuroNEXT Clinical Trial Network and on behalf of the NN101 SMA Biomarker Investigators. 2016. Baseline results of the NeuroNEXT spinal muscular atrophy infant biomarker study. Ann Clin Transl Neurol 3(2): 132-145.. PMID: 26900585
Kolb, SJ, Coffey, CS, Yankey, JW et al. 2016. Baseline results of the NeuroNext spinal muscular atrophy infant biomarker study. Annals of Clinical and Translational Neurology, 21 January 2016;1-14.
Arnold WD, Duque S, Iyer CC, Zaworski P, McGovern VL, Taylor SJ, von Herrmann KM, Kobayashi DT, Chen KS, Kolb SJ, Paushkin SV, Burghes AH. 2016. Normalization of Patient-Identified Plasma Biomarkers in SMNΔ7 Mice following Postnatal SMN Restoration. PLoS One. 2016 Dec 1;11(12):e0167077. doi: 10.1371/journal.pone.0167077. eCollection 2016.. PMID: 27907033
Czech C, Tang W, Bugawan T, Mano C, Horn C, Iglesias VA, Fröhner S, Zaworski PG, Paushkin S, Chen K, Kremer T. 2015. Biomarker for Spinal Muscular Atrophy: Expression of SMN in Peripheral Blood of SMA Patients and Healthy Controls. PLoS One 10(10): e0139950.. PMID: 26468953
Iyer, CC, McGovern, VL, Murray, JD, Gombash, SE, Zaworski, PG, Foust, KD, Janssen, PM and Burghes, AH. 2015. Low levels of survival motor neuron protein are sufficient for normal muscle function in the SMNdelta7 mouse model of SMA. Hum Mol Genet 2015;24(21):6160-73. PMID: 26276812
McGovern, VL, Iyer, CC, Arnold, WD, Gombash, SE, Zaworski, PG, Blatnik, AJ, Foust, KD and Burghes, AH. 2015. SMN expression is required in motor neurons to rescue electrophysiological deficits in the SMNdelta7 mouse model of SMA. Hum Mol Genet 2015; 24(19):5524-41. PMID: 26206889
Li J, Geisbush TR, Arnold WD, Rosen GD, Zaworski PG, Rutkove SB. 2014. A Comparison of Three Electrophysiological Methods for the Assessment of Disease Status in a Mild Spinal Muscular Atrophy Mouse Model. PLoS One 9(10): e111428..
Cherry JJ, Kobayashi DT, Lynes MM, Naryshkin NN, Tiziano FD, Zaworski PG, Rubin LL, Jarecki J. 2014. Assays for the Identification and Prioritization of Drug Candidates for Spinal Muscular Atrophy. Assay Drug Dev Technol 12(6): 315-341.. PMID: 25147906
Kobayashi DT, Decker D, Zaworski P, Klott K, McGonigal J, Ghazal N, Sly L, Chung B, Vanderlugt J, Chen KS. 2012. Evaluation of peripheral blood mononuclear cell processing and analysis for Survival Motor Neuron protein. PLoS One. 2012;7(11):e50763. PMID: 23226377
Ho SB, Luu Y, Shekels LL, Batra SK, Kandarian B, Evans DB, Zaworski PG, Wolfe CL, Heinrikson RL. 2010. Activity of recombinant cysteine-rich domain proteins derived from the membrane-bound MUC17/Muc3 family mucins. Biochim Biophys Acta 1800(7):629-38. Epub 2010 Mar 20.. PMID: 20332014
Stroke, IL, Letourneau, JJ, Miller, TE, Xu, Y, Pechik, I, Savoly, DR, Ma, L, Sturzenbecker, LJ, Sabalski, J, Stein, PD, Webb, ML, Hilbert, DW. 2018. Treatment of Clostridium difficile infection with a small molecule inhibitor of toxin UDP-glucose hydrolysis activity. Antimicrob. Agents Chemother. (2018), 62, e00107-18.
Letourneau, JJ, Stroke, IL, Hilbert, DW, Sturzenbecker, LJ, Marinelli, BA, Quintero, JG, Sabalski, J, Ma, L, Diller, DJ, Stein, PD, Webb, ML. 2018. Identification and initial optimization of inhibitors of Clostridium difficile (C. difficile) toxin B (TcdB). Bioorganic & Medicinal Chemistry Letters (2018), 28(4), 756-7.
Stroke, IL, Ma, L, Letourneau, JJ, Cole, AG, Li, Y, Marinelli, BA, Malone, J, Paulish-Miller, T, Pechik, I, Quintero, JG, Sabalski, JE, Savoly, DR, Wang, A, Hilbert, DW, Gygax, S, Miller, DK, Stein, P, Webb, M. 2015. Miniaturized assays for RhoA inactivation through glucosylation by Clostridium difficile toxin. Society for Laboratory Automation and Screening 4th Annual Conference and Exhibition (Washington, D.C.) 7-11 February, 2015.
Gallo-Ebert C, Donigan M, Stroke IL, Swanson RN, Manners MT, Francisco J, Toner G, Gallagher D, Huang C-Y, Gygax SE, Webb M, Nickels JT Jr. 2014. Novel Antifungal Drug Discovery Based On Targeting Pathways Regulating The Fungal-Conserved Upc2 Transcription Factor. Antimicrob. Agents Chemother. (2014), 58(1), 258-266.
Beasley, JR, Huang, C-Y, Gallo-Ebert, C, Bata, A, Donigan, M, Giordano, C, Kanneganti, N, Malone, J, Sieber-McMaster, E, Nawoschik, S, O'Brien, L, Pham, Q, Severinova, E, Shi, D, Swanson, R, Tovar, K, Xu, X, Zalamea, P, Nickels, J, Stein, P., Webb, MW. 2013. Discovery and Optimization of GPBAR1 (TGR5) Agonists. Society for Laboratory Automation and Screening 2nd Annual Conference and Exhibition (Orlando, Florida) 12-16 January 2013.
Uveges, A, Severinova, E, Gallagher, D, Kanneganti, N, McQueney, M, Swanson, R . 2013. A Robust Ultra-High-Throughput Screening Assay for DEK Binding to DNA. Society for Laboratory Automation and Screening 2nd Annual Conference and Exhibition (Orlando, Florida) 12-16 January, 2013.
Stroke, IL, Sturzenbecker, LJ, Letourneau, JJ, Quintero, JG, Sabalski, Joan E, Marinelli, B, Pechik, I, Diller, D, Paulish-Miller, T, Hilbert, DW., Gygax, S, Stein, P, Webb, M. 2013. High throughput screening of combinatorial libraries for inhibitors of Clostridium difficile toxins. Society for Laboratory Automation and Screening 2nd Annual Conference and Exhibition (Orlando, Florida) 12-16 January, 2013.
Stein, P. 2013. Simple and Complex Science and Technology. Rutgers University, November 21, 2013.
McQueney, MS, Uveges, A, Malone, J, O’Brien, L, Cole, A, Webb, M. 2012. An Ultra High Throughput Screen of the Venenum Discovery Library for PARP-1 Inhibitors for The 17th International Inflammation Research Association Conference (Lake George, New York) 9-13 September, 2012.
Stroke, IL, Hilbert, DW, Letourneau, JJ, Paulish-Miller, T, Quintero, JG, Sabalski, JE. 2012. Identification and Characterization of Small Molecules Targeting Clostridium difficile. Society for Laboratory Automation and Screening (San Diego, California) 6-8 February, 2012.
Beasley, JR, Malone, J, O’Brien, L, Huang, C, Sieber-McMaster, E, Shi, D, Xu, X, Nawoschik, S, Pham, Q, Webb, M. 2012. Discovery of GPBAR1 (TGR5) Agonists from a 1536-well UHTS of the ECLiPS Compound Collection. Society for Laboratory Automation and Screening (San Diego, California) 6-8 February, 2012.
Stroke IL, Hilbert DW, Letourneau JJ, Paulish-Miller T, Quintero JG, Sabalski JE. 2012. Identification and Characterization of Small Molecules Targeting Clostridium difficile. Society for Laboratory Automation and Screening (San Diego, California) 6-8 February, 2012.
Webb, M. 2012. How to Mine Novel Biology Space with Technology Picks and Shovels. Kean University, March 12, 2012.
Webb, M. 2012. The Pivitol Role of Vertical Integration in Biotechnology. Rutgers University, November 5, 2012.
Kruijf PD, Lim HD, Roumen L, Renjaan VA, Zhao J, Webb ML, Auld DS, Wijkmans JCHM, Zaman GJR, Smit MJ, Graaf CD, Leurs R. 2011. Identification of a Novel Allosteric Binding Site in the CXCR2. Chemokine Recept Mol Pharmacol 80:1108-1118. PMID: 21948388
Huang C, Zhao J, Simhadri S, Webb M, Ohlmeyer M, Zhi L. 2011. Discovery of a Novel Series of mGluR5 Antagonists. Gordon Research Conference, Medicinal Chemistry, Colby- Sawyer College, New London, NH, August 7-12, 2011.
Swanson, RN, Stroke, IL, Manners, MT, Gallo-Ebert, C, Nickels, J. 2011. Engineering Transcription Factors for Use in Ultra-High Throughput DNA Binding Assays. 7th Annual Protein Engineering Summit (Boston, Massachusetts) 9-13 May, 2011.
Stroke, IL, Manners, MT, Swanson, RN, Dimitrov, D, Gallo-Ebert, C, Nickels, J. 2011. Targeting the Transcription Factor Upc2 for Antifungal Drug Discovery. Society for Biomolecular Sciences Annual Meeting (Orlando, Florida) 16-31 March, 2011.