GD3 is a fully integrated, full-service contract research organization (CRO) focused on providing services to support preclinical drug discovery and development. We leverage decades of Pharma and CRO experience and expertise to advance your therapeutic programs to the benefit of patients and their physicians. GD3 has a diverse portfolio that covers all areas of preclinical drug discovery and development, including discovery biology, synthetic organic and medicinal chemistry, DMPK, in vivo pharmacology, disease models, and toxicology.
Chemistry Division
GD3 Chemistry Division specializes in synthetic organic and medicinal chemistry. We offer expert services in drug discovery, process chemistry, and custom synthesis. Our team of innovative chemists has a proven track record of successfully managing and executing drug discovery programs at all stages for diverse industries and institutions. From early lead identification through clinical development, GD3 Chemistry possesses the experience and resources to handle a wide range of drug discovery projects. Our highly trained chemists, with their deep industry experience, work in state-of-the-art laboratories equipped with the latest technology. At GD3 Chemistry, we are committed to providing custom solutions for even the most complex chemistry challenges.
Disease Modeling Division
GD3 Disease Modeling Division accelerates translational research by evaluating therapeutic candidates in rodent models of human disease. We offer both customized and standard preclinical in vivo pharmacology services, including new model development and validation. Our expanding collection features over 150 unique, well-characterized PDX models. Operating within an AAALAC-accredited facility, our team of experienced scientists understands the complexities of preclinical drug development. From study design and model development to comprehensive data analysis, GD3 efficiently assesses your needs, executes your studies, and delivers clear, concise reports. Our expertise spans diverse therapeutic modalities, including small molecules, biologics, and cell therapies. GD3's commitment to high-quality data and flexible services ensures the efficient and successful progression of your drug development program.
Biochemistry & Bioanalytical Division
GD3 Biochemistry and Bioanalytical Division offers comprehensive GLP and non-GLP bioanalytical services, leveraging the expertise of seasoned scientists, state-of-the-art technology, and diverse platforms. We specialize in pharmacokinetic (PK) and toxicokinetic (TK) evaluations for pharmaceutical and biopharmaceutical products, employing advanced techniques such as LC-MS/MS, immunoassay, and qPCR. Collaborating closely with our clients, we tailor bioanalytical strategies to meet specific project needs and budgets. Our streamlined workflow, encompassing sample login, study scheduling, analysis, and reporting, adheres to best practices and ensures the highest quality, compliance, and regulatory standards for all delivered data.
Preclinical-Toxicology Division
GD3 Preclinical-Toxicology Division offers comprehensive GLP and non-GLP preclinical research services, including toxicology, efficacy, pharmacology, pharmacokinetics/pharmacodynamics, histopathology, and safety studies across all common laboratory species. Our specialized expertise encompasses a wide range of therapeutic areas, including ocular, dermatology, fibrosis, otic/ototoxicity, wound healing, burns, stem cell research, oncology, renal, ophthalmology, inflammation, immune-mediated models, cardiovascular and pulmonary studies, and infection models and devices. We also provide contract histopathology, immunohistochemistry, and custom model development. Our state-of-the-art, AAALAC-accredited facility is registered with the FDA, USDA, and OLAW.